Beneficial Effects of Vagal Stimulation and Bradycardia During Experimental Acute Myocardial Ischemia
نویسندگان
چکیده
منابع مشابه
Beneficial effects of vagal stimulation and bradycardia during experimental acute myocardial ischemia.
It is commonly believed that vagally-mediated bradyeardia predisposes to ventricular fibrillation (VF) during acute myocardial ischemia. Recent experimental studies, however, have shown that bradycardia and vagal stimulation independently raise the threshold for electrically induced VF in the ischemic canine heart. To determine the influence of vagal stimulation on the spontaneous development o...
متن کاملBeneficial Effects of Vagal Stimulation and Bradyeardia During Experimental Acute Myocardial Ischemia
It is commonly believed that vagally-mediated bradyeardia predisposes to ventricular fibrillation (VF) during acute myocardial ischemia. Recent experimental studies, however, have shown that bradycardia and vagal stimulation independently raise the threshold for electrically induced VF in the ischemic canine heart. To determine the influence of vagal stimulation on the spontaneous development o...
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The effects of intravenous administration of iloprost, a prostacyclin analogue, on myocardial energy metabolism and myocardial blood flow (MBF) were examined in anesthetized open-chest dogs subjected to 60 min of myocardial ischemia by coronary ligation. Iloprost administration at levels of 0.1 or 0.2 micrograms/kg/min was started 30 min before the commencement of ischemia and continued through...
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This study was designed to determine whether coronary collaterals have preventive effects on tachycardia-induced myocardial ischemia under partial restriction of proximal coronary artery inflow. Studies were carried out in dogs with developed coronary collaterals and control dogs. ST-elevation in epicardial and intramyocardial electrograms was used for assessing the degree of regional myocardia...
متن کاملThe effects of heart rate, myocardial ischemia and vagal stimulation on the threshold for ventricular fibrillation.
The minimum current required to cause ventricular fibrillation was determined by electrical stimulation of the normal or ischemic canine left ventricle. The threshold for ventricular fibrillation in the normal heart decreased when the heart rate was rapid. Strong vagal stimulation did not affect the ventricular fibrillation threshold when the heart rate was fixed. The fall in the ventricular fi...
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ژورنال
عنوان ژورنال: Circulation
سال: 1974
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.49.5.943